About 7 results found for searched term "Auristatin E" (0.095 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3741 | Monomethyl auristatin E | Microtubule |
| MMAE, Vedotin; SGD-1010 | ||
| Monomethyl auristatin E (MMAE; Vedotin) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin.*The compound is unstable in solutions, freshly prepared is recommended | ||
| M9818 | Auristatin E | Microtubule |
| Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. | ||
| M10398 | Mc-MMAE | Drug-Linker Conjugates for ADC |
| Maleimidocaproyl-monomethylauristatin E | ||
| Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a drug-linker conjugate for ADC. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M13452 | MMAF-OMe | Others |
| Monomethyl auristatin F methyl ester | ||
| MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively. | ||
| M13688 | Soblidotin | Microtubule |
| Auristatin PE; TZT-1027 | ||
| Soblidotin (Auristatin PE) is a novel synthetic Dolastatin 10 derivative and inhibitor of tubulin polymerization. | ||
| M13690 | MMAE-d8 | Microtubule |
| Monomethyl auristatin E-d8; Deuterated labeled MMAE | ||
| D8-MMAE (D8-Monomethyl auristatin E) is a deuterated labeled MMAE, a potent mitotic inhibitor and a tubulin inhibitor. | ||
| M13692 | MMAF hydrochloride | Microtubule |
| Monomethylauristatin F hydrochloride | ||
| MMAF (Monomethylauristatin F) hydrochloride is a potent tubulin polymerization inhibitor and is used as a antitumor agent. | ||
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